Unlocking phenotypic plasticity provides novel insights for immunity and personalized therapy in lung adenocarcinoma

Background: Unlocking phenotype plasticity (UPP) has been shown to have an essential role in the mechanism of tumor development and therapeutic response.However, the clinical significance of unlocking phenotypic plasticity in patients with lung adenocarcinoma is unclear.This study aimed to explore the roles of unlocking phenotypic plasticity in imm

read more

2-Amino-1-(2-carboxylatoethyl)pyrimidin-1-ium monohydrate

In the title structure, C7H9N3O2·H2O, there are two formula units in the asymmetric unit.The molecule is a zwitterion, Ashtrays containing a quaternary N atom and a deprotonated carboxyl group, with C—O distances in the range 1.256 (2)–1.266 (3) Å.The two independent molecules form

read more

Stereotactic Body Radiation Therapy for Prostate Cancer: Review of Experience of a Multicenter Phase I/II Dose Escalation Study

Introduction: Stereotactic body radiation therapy (SBRT) is an area of active investigation for treatment of prostate cancer.In our phase I dose escalation study maximum tolerated dose was not reached, and subsequently phase II study has been completed.The purpose of this article is to review our experiences of dose escalated SBRT for localized pro

read more